A cationic polymethacrylate-copolymer acts as an agonist for β-amyloid and an antagonist for amylin fibrillation

In humans, β-amyloid and islet amyloid polypeptide (IAPP, also known as amylin) aggregations are linked to Alzheimer's disease and type-2 diabetes, respectively. There is significant interest in better understanding the aggregation process by using chemical tools. Here, we show the ability of a...

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Detalles Bibliográficos
Autores principales: Sahoo, Bikash R., Genjo, Takuya, Nakayama, Takahiro W., Stoddard, Andrea K., Ando, Toshio, Yasuhara, Kazuma, Fierke, Carol A., Ramamoorthy, Ayyalusamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457205/
https://www.ncbi.nlm.nih.gov/pubmed/31015938
http://dx.doi.org/10.1039/c8sc05771k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457205/
https://www.ncbi.nlm.nih.gov/pubmed/31015938
http://dx.doi.org/10.1039/c8sc05771k

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