Dyslipidemia-associated atherogenic oxidized lipids induce platelet hyperactivity through phospholipase Cγ2-dependent reactive oxygen species generation

Oxidized low-density lipoprotein (oxLDL) and associated oxidized phosphocholine-headgroup phospholipids (oxPCs) activate blood platelets through ligation of the scavenger receptor CD36. Previously, we found that oxLDL stimulated phosphorylation of phospholipase Cγ2 (PLCγ2). However, the functional r...

Descripción completa

Detalles Bibliográficos
Autores principales: Berger, Martin, Wraith, Katie, Woodward, Casey, Aburima, Ahmed, Raslan, Zaher, Hindle, Matthew S., Moellmann, Julia, Febbraio, Maria, Naseem, Khalid M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457275/
https://www.ncbi.nlm.nih.gov/pubmed/29733744
http://dx.doi.org/10.1080/09537104.2018.1466386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457275/
https://www.ncbi.nlm.nih.gov/pubmed/29733744
http://dx.doi.org/10.1080/09537104.2018.1466386

Ejemplares similares