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Controlling a burn: outer-sphere gating of hydroxylamine oxidation by a distal base in cytochrome P460

Ammonia oxidizing bacteria (AOB) use the cytotoxic, energetic molecule hydroxylamine (NH(2)OH) as a source of reducing equivalents for cellular respiration. Despite disproportionation or violent decomposition being typical outcomes of reactions of NH(2)OH with iron, AOB and anammox heme P460 protein...

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Detalles Bibliográficos
Autores principales: Smith, Meghan A., Majer, Sean H., Vilbert, Avery C., Lancaster, Kyle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457333/
https://www.ncbi.nlm.nih.gov/pubmed/31015919
http://dx.doi.org/10.1039/c9sc00195f