Ancestral sequences from an elite neutralizer proximal to the development of neutralization resistance as a potential source of HIV vaccine immunogens

A major challenge in HIV vaccine development is the identification of immunogens able to elicit broadly neutralizing antibodies (bNAbs). While remarkable progress has been made in the isolation and characterization of bNAbs, the epitopes they recognize appear to be poorly immunogenic. Thus, none of...

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Detalles Bibliográficos
Autores principales: Mesa, Kathryn A., Yu, Bin, Wrin, Terri, Petropoulos, Christos J., Pogson, Grant H., Alexander, David L., Perez, Gerardo, O’Rourke, Sara M., Sinangil, Faruk, Robinson, Joseph, Conant, Marcus A., Berman, Phillip W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457492/
https://www.ncbi.nlm.nih.gov/pubmed/30969970
http://dx.doi.org/10.1371/journal.pone.0213409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457492/
https://www.ncbi.nlm.nih.gov/pubmed/30969970
http://dx.doi.org/10.1371/journal.pone.0213409

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