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A lipid-free and insulin-supplemented medium supports De Novo fatty acid synthesis gene activation in melanoma cells

While investigating the role played by de novo lipid (DNL) biosynthesis in cancer cells, we sought a medium condition that would support cell proliferation without providing any serum lipids. Here we report that a defined serum free cell culture medium condition containing insulin, transferrin and s...

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Detalles Bibliográficos
Autores principales: Wu, Su, Näär, Anders M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457551/
https://www.ncbi.nlm.nih.gov/pubmed/30970006
http://dx.doi.org/10.1371/journal.pone.0215022