Comparative analysis of homologous aminopeptidase PepN from pathogenic and non-pathogenic mycobacteria reveals divergent traits

Mycobacterium tuberculosis (Mtb) secretes proteases and peptidases to subjugate its host. Out of its sixty plus proteases, atleast three are reported to reach host macrophages. In this study, we show that Mtb also delivers a lysyl alanine aminopeptidase, PepN (Rv2467) into host macrophage cytosol. O...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Sharma, Nishant, Aggarwal, Suruchi, Kumar, Saravanan, Sharma, Rahul, Choudhury, Konika, Singh, Niti, Jayaswal, Praapti, Goel, Renu, Wajid, Saima, Yadav, Amit Kumar, Atmakuri, Krishnamohan
Aineistotyyppi: Online Artikkeli Teksti
Kieli:English
Julkaistu: Public Library of Science 2019
Aiheet:
Research Article
Linkit:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457555/
https://www.ncbi.nlm.nih.gov/pubmed/30969995
http://dx.doi.org/10.1371/journal.pone.0215123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457555/
https://www.ncbi.nlm.nih.gov/pubmed/30969995
http://dx.doi.org/10.1371/journal.pone.0215123

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