Comparative analysis of homologous aminopeptidase PepN from pathogenic and non-pathogenic mycobacteria reveals divergent traits

Mycobacterium tuberculosis (Mtb) secretes proteases and peptidases to subjugate its host. Out of its sixty plus proteases, atleast three are reported to reach host macrophages. In this study, we show that Mtb also delivers a lysyl alanine aminopeptidase, PepN (Rv2467) into host macrophage cytosol. O...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Sharma, Nishant, Aggarwal, Suruchi, Kumar, Saravanan, Sharma, Rahul, Choudhury, Konika, Singh, Niti, Jayaswal, Praapti, Goel, Renu, Wajid, Saima, Yadav, Amit Kumar, Atmakuri, Krishnamohan
Μορφή: Online Άρθρο Κείμενο
Γλώσσα:English
Έκδοση: Public Library of Science 2019
Θέματα:
Research Article
Διαθέσιμο Online:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457555/
https://www.ncbi.nlm.nih.gov/pubmed/30969995
http://dx.doi.org/10.1371/journal.pone.0215123

Διαδίκτυο

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457555/
https://www.ncbi.nlm.nih.gov/pubmed/30969995
http://dx.doi.org/10.1371/journal.pone.0215123

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