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Crystal structure of the SH3 domain of human Lyn non-receptor tyrosine kinase

Lyn kinase (Lck/Yes related novel protein tyrosine kinase) belongs to the family of Src-related non-receptor tyrosine kinases. Consistent with physiological roles in cell growth and proliferation, aberrant function of Lyn is associated with various forms of cancer, including leukemia, breast cancer...

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Detalles Bibliográficos
Autores principales: Berndt, Sandra, Gurevich, Vsevolod V., Iverson, T. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457566/
https://www.ncbi.nlm.nih.gov/pubmed/30969999
http://dx.doi.org/10.1371/journal.pone.0215140