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Absence of p21((WAF1/CIP1/SDI1)) protects against osteopenia and minimizes bone loss after ovariectomy in a mouse model
p21((WAF1/CIP1/SDI1)) is a critical sentinel of the cell cycle that plays an important role in determining cell fate with respect to proliferation, differentiation and apoptosis. Recent studies have demonstrated that inhibition/loss of p21 promotes osteo-chondro differentiation in progenitor/stem ce...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457871/ https://www.ncbi.nlm.nih.gov/pubmed/30970032 http://dx.doi.org/10.1371/journal.pone.0215018 |