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Absence of p21((WAF1/CIP1/SDI1)) protects against osteopenia and minimizes bone loss after ovariectomy in a mouse model

p21((WAF1/CIP1/SDI1)) is a critical sentinel of the cell cycle that plays an important role in determining cell fate with respect to proliferation, differentiation and apoptosis. Recent studies have demonstrated that inhibition/loss of p21 promotes osteo-chondro differentiation in progenitor/stem ce...

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Detalles Bibliográficos
Autores principales: Premnath, Priyatha, Ferrie, Leah, Louie, Dante, Boyd, Steven, Krawetz, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457871/
https://www.ncbi.nlm.nih.gov/pubmed/30970032
http://dx.doi.org/10.1371/journal.pone.0215018