A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike

Continuously emerging highly pathogenic human coronaviruses (HCoVs) remain a major threat to human health, as illustrated in past SARS-CoV and MERS-CoV outbreaks. The development of a drug with broad-spectrum HCoV inhibitory activity would address this urgent unmet medical need. Although previous st...

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Detalles Bibliográficos
Autores principales: Xia, Shuai, Yan, Lei, Xu, Wei, Agrawal, Anurodh Shankar, Algaissi, Abdullah, Tseng, Chien-Te K., Wang, Qian, Du, Lanying, Tan, Wenjie, Wilson, Ian A., Jiang, Shibo, Yang, Bei, Lu, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457931/
https://www.ncbi.nlm.nih.gov/pubmed/30989115
http://dx.doi.org/10.1126/sciadv.aav4580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457931/
https://www.ncbi.nlm.nih.gov/pubmed/30989115
http://dx.doi.org/10.1126/sciadv.aav4580

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