Reconstructing recent population history while mapping rare variants using haplotypes

Haplotype-based methods are a cost-effective alternative to characterize unobserved rare variants and map disease-associated alleles. Moreover, they can be used to reconstruct recent population history, which shaped distribution of rare variants and thus can be used to guide gene mapping studies. In...

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Detalles Bibliográficos
Autores principales: Yunusbaev, Ural, Valeev, Albert, Yunusbaeva, Milyausha, Kwon, Hyung Wook, Mägi, Reedik, Metspalu, Mait, Yunusbayev, Bayazit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458133/
https://www.ncbi.nlm.nih.gov/pubmed/30971755
http://dx.doi.org/10.1038/s41598-019-42385-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458133/
https://www.ncbi.nlm.nih.gov/pubmed/30971755
http://dx.doi.org/10.1038/s41598-019-42385-6

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