Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition

Lung cancer is the leading cause of cancer-related deaths worldwide. Tumor suppressor genes remain to be systemically identified for lung cancer. Through the genome-wide screening of tumor-suppressive transcription factors, we demonstrate here that GATA4 functions as an essential tumor suppressor in...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Lei, Hu, Yong, Tian, Yahui, Fan, Zhenzhen, Wang, Kun, Li, Hongdan, Zhou, Qian, Zeng, Guandi, Hu, Xin, Yu, Lei, Zhou, Shiyu, Tong, Xinyuan, Huang, Hsinyi, Chen, Haiquan, Liu, Qingsong, Liu, Wanting, Zhang, Gong, Zeng, Musheng, Zhou, Guangbiao, He, Qingyu, Ji, Hongbin, Chen, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458308/
https://www.ncbi.nlm.nih.gov/pubmed/30971692
http://dx.doi.org/10.1038/s41467-019-09295-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458308/
https://www.ncbi.nlm.nih.gov/pubmed/30971692
http://dx.doi.org/10.1038/s41467-019-09295-7

Ejemplares similares