Pathway centrality in protein interaction networks identifies putative functional mediating pathways in pulmonary disease

Identification of functional pathways mediating molecular responses may lead to better understanding of disease processes and suggest new therapeutic approaches. We introduce a method to detect such mediating functions using topological properties of protein-protein interaction networks. We define t...

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Detalles Bibliográficos
Autores principales: Park, Jisoo, Hescott, Benjamin J., Slonim, Donna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458310/
https://www.ncbi.nlm.nih.gov/pubmed/30971743
http://dx.doi.org/10.1038/s41598-019-42299-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458310/
https://www.ncbi.nlm.nih.gov/pubmed/30971743
http://dx.doi.org/10.1038/s41598-019-42299-3

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