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Pathway centrality in protein interaction networks identifies putative functional mediating pathways in pulmonary disease
Identification of functional pathways mediating molecular responses may lead to better understanding of disease processes and suggest new therapeutic approaches. We introduce a method to detect such mediating functions using topological properties of protein-protein interaction networks. We define t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458310/ https://www.ncbi.nlm.nih.gov/pubmed/30971743 http://dx.doi.org/10.1038/s41598-019-42299-3 |