Detection of ERBB2 (HER2) Gene Amplification Events in Cell-Free DNA and Response to Anti-HER2 Agents in a Large Asian Cancer Patient Cohort

Background: HER2 antagonists have marked activity and are approved for the treatment of HER2 overexpressing breast and gastric cancers. Recent studies have shown that ERBB2 (HER2) gene amplification and overexpression may also be actionable in other tumor types. Inter- and intratumoral heterogeneity...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Jeeyun, Franovic, Aleksandra, Shiotsu, Yukimasa, Kim, Seung Tae, Kim, Kyoung-Mee, Banks, Kimberly C., Raymond, Victoria M., Lanman, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458313/
https://www.ncbi.nlm.nih.gov/pubmed/31019892
http://dx.doi.org/10.3389/fonc.2019.00212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458313/
https://www.ncbi.nlm.nih.gov/pubmed/31019892
http://dx.doi.org/10.3389/fonc.2019.00212

Ejemplares similares