Ets1 Plays a Critical Role in MLL/EB1-Mediated Leukemic Transformation in a Mouse Bone Marrow Transplantation Model

Leukemogenic potential of MLL fusion with the coiled-coil domain-containing partner genes and the downstream target genes of this type of MLL fusion have not been clearly investigated. In this study, we demonstrated that the coiled-coil–four-helix bundle structure of EB1 that participated in the MLL...

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Detalles Bibliográficos
Autores principales: Fu, Jen-Fen, Yen, Tzung-Hai, Huang, Ying-Jung, Shih, Lee-Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458341/
https://www.ncbi.nlm.nih.gov/pubmed/30974389
http://dx.doi.org/10.1016/j.neo.2019.03.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458341/
https://www.ncbi.nlm.nih.gov/pubmed/30974389
http://dx.doi.org/10.1016/j.neo.2019.03.006

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