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Ets1 Plays a Critical Role in MLL/EB1-Mediated Leukemic Transformation in a Mouse Bone Marrow Transplantation Model
Leukemogenic potential of MLL fusion with the coiled-coil domain-containing partner genes and the downstream target genes of this type of MLL fusion have not been clearly investigated. In this study, we demonstrated that the coiled-coil–four-helix bundle structure of EB1 that participated in the MLL...
Autores principales: | Fu, Jen-Fen, Yen, Tzung-Hai, Huang, Ying-Jung, Shih, Lee-Yung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458341/ https://www.ncbi.nlm.nih.gov/pubmed/30974389 http://dx.doi.org/10.1016/j.neo.2019.03.006 |
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