Structures of TRPV2 in distinct conformations provide insight into role of the pore turret

Cation channels of the TRP family serve important physiological roles by opening in response to diverse intra-and extra-cellular stimuli which regulate their lower or upper gates. Despite extensive studies, the mechanism coupling these gates has remained obscure. Previous structures have failed to r...

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Detalles Bibliográficos
Autores principales: Dosey, Timothy L., Wang, Zhao, Fan, Guizhen, Zhang, Zhixian, Serysheva, Irina I., Chiu, Wah, Wensel, Theodore G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458597/
https://www.ncbi.nlm.nih.gov/pubmed/30598551
http://dx.doi.org/10.1038/s41594-018-0168-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458597/
https://www.ncbi.nlm.nih.gov/pubmed/30598551
http://dx.doi.org/10.1038/s41594-018-0168-8

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