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Structures of TRPV2 in distinct conformations provide insight into role of the pore turret
Cation channels of the TRP family serve important physiological roles by opening in response to diverse intra-and extra-cellular stimuli which regulate their lower or upper gates. Despite extensive studies, the mechanism coupling these gates has remained obscure. Previous structures have failed to r...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458597/ https://www.ncbi.nlm.nih.gov/pubmed/30598551 http://dx.doi.org/10.1038/s41594-018-0168-8 |