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Effects of a previously selected antibiotic resistance on mutations acquired during development of a second resistance in Escherichia coli
BACKGROUND: The effect of mutations conferring antibiotic resistance can depend on the genetic background. To determine if a previously de novo acquired antibiotic resistance influences the adaptation to a second antibiotic, antibiotic resistance was selected for by exposure to stepwise increasing s...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458618/ https://www.ncbi.nlm.nih.gov/pubmed/30975082 http://dx.doi.org/10.1186/s12864-019-5648-7 |