Effects of a previously selected antibiotic resistance on mutations acquired during development of a second resistance in Escherichia coli

BACKGROUND: The effect of mutations conferring antibiotic resistance can depend on the genetic background. To determine if a previously de novo acquired antibiotic resistance influences the adaptation to a second antibiotic, antibiotic resistance was selected for by exposure to stepwise increasing s...

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Detalles Bibliográficos
Autores principales: Hoeksema, Marloes, Jonker, Martijs J., Brul, Stanley, ter Kuile, Benno H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458618/
https://www.ncbi.nlm.nih.gov/pubmed/30975082
http://dx.doi.org/10.1186/s12864-019-5648-7

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