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Exosomes secreted by mesenchymal stromal/stem cell-derived adipocytes promote breast cancer cell growth via activation of Hippo signaling pathway

OBJECTIVE: Although adipocytes are the most abundant stromal cell component in breast cancer tissues, their interaction with breast cancer cells has been less investigated compared to cancer-associated fibroblasts or macrophages. Exosomes are a novel way of cell-cell communication and have been demo...

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Detalles Bibliográficos
Autores principales: Wang, Shihua, Su, Xiaodong, Xu, Meiqian, Xiao, Xian, Li, Xiaoxia, Li, Hongling, Keating, Armand, Zhao, Robert Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458638/
https://www.ncbi.nlm.nih.gov/pubmed/30971292
http://dx.doi.org/10.1186/s13287-019-1220-2