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Continuation versus discontinuation of treatment for severe dementia: randomized, pragmatic, open-label, clinical trial to evaluate the efficacy of continuing drug treatment in patients with severe dementia (STOP-DEM)

BACKGROUND: Previous observational studies and clinical trials have shown that cholinesterase inhibitors (with or without memantine) provide benefit for patients with mild-to-moderate Alzheimer’s disease. However, the impact of treatment continuation after progression to severe disease is unknown. T...

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Detalles Bibliográficos
Autores principales: Soler, Aina, Amer, Guillem, Leiva, Alicia, Ripoll, Joana, Llorente, María Angeles, Leiva, Alfonso, Taltavull, Joana Maria, Molina, Rosa, Llobera, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458648/
https://www.ncbi.nlm.nih.gov/pubmed/30971215
http://dx.doi.org/10.1186/s12877-019-1122-2