Targeting p21-activated kinase 1 inhibits growth and metastasis via Raf1/MEK1/ERK signaling in esophageal squamous cell carcinoma cells

BACKGROUND: p21-activated kinase 1 (PAK1) plays a fundamental role in promoting the development and progression of several cancers and is a potential therapeutic target. However, the biological function and underlying mechanism of PAK1 in esophageal squamous cell carcinoma (ESCC) remain unclear. MET...

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Detalles Bibliográficos
Autores principales: Chen, Liang, Bi, Shuning, Hou, Jiuzhou, Zhao, Zhijun, Wang, Chaojie, Xie, Songqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458688/
https://www.ncbi.nlm.nih.gov/pubmed/30971268
http://dx.doi.org/10.1186/s12964-019-0343-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458688/
https://www.ncbi.nlm.nih.gov/pubmed/30971268
http://dx.doi.org/10.1186/s12964-019-0343-5

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