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Targeting p21-activated kinase 1 inhibits growth and metastasis via Raf1/MEK1/ERK signaling in esophageal squamous cell carcinoma cells

BACKGROUND: p21-activated kinase 1 (PAK1) plays a fundamental role in promoting the development and progression of several cancers and is a potential therapeutic target. However, the biological function and underlying mechanism of PAK1 in esophageal squamous cell carcinoma (ESCC) remain unclear. MET...

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Detalles Bibliográficos
Autores principales:	Chen, Liang, Bi, Shuning, Hou, Jiuzhou, Zhao, Zhijun, Wang, Chaojie, Xie, Songqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458688/ https://www.ncbi.nlm.nih.gov/pubmed/30971268 http://dx.doi.org/10.1186/s12964-019-0343-5

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