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Study protocol: exploring the efficacy of cyclophosphamide added to corticosteroids for treating acute exacerbation of idiopathic pulmonary fibrosis; a randomized double-blind, placebo-controlled, multi-center phase III trial (EXAFIP)

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease, with a median survival of 2–3 years and variable natural history, characterized by gradual and progressive deterioration. Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is a severe complication, associated with po...

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Detalles Bibliográficos
Autores principales: Naccache, Jean-Marc, Montil, Melissa, Cadranel, Jacques, Cachanado, Marine, Cottin, Vincent, Crestani, Bruno, Valeyre, Dominique, Wallaert, Benoit, Simon, Tabassome, Nunes, Hilario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458697/
https://www.ncbi.nlm.nih.gov/pubmed/30971235
http://dx.doi.org/10.1186/s12890-019-0830-x