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Salicylic acid amplifies Carbachol-induced bronchoconstriction in human precision-cut lung slices

BACKGROUND: Asthma exacerbations evoke emergency room visits, progressive loss of lung function and increased mortality. Environmental and industrial toxicants exacerbate asthma, although the underlying mechanisms are unknown. We assessed whether 3 distinct toxicants, salicylic acid (SA), toluene di...

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Detalles Bibliográficos
Autores principales: Jude, Joseph, Botelho, Danielle, Karmacharya, Nikhil, Cao, Gao Yuan, Jester, William, Panettieri, Reynold A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458705/
https://www.ncbi.nlm.nih.gov/pubmed/30971247
http://dx.doi.org/10.1186/s12931-019-1034-x