Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner

BACKGROUND: Metabolic reprogramming is one of the hallmarks of cancer cells. The pentose phosphate pathway (PPP), a branch of glycolysis, is an important metabolic pathway for the survival and biosynthesis of cancer cells. Transketolase (TKT) is a key enzyme in the non-oxidative phase of PPP. The me...

Descripción completa

Detalles Bibliográficos
Autores principales: Qin, Zhaoyu, Xiang, Chan, Zhong, Fan, Liu, Yang, Dong, Qiongzhu, Li, Kai, Shi, Wenhao, Ding, Chen, Qin, Lunxiu, He, Fuchu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458711/
https://www.ncbi.nlm.nih.gov/pubmed/30971297
http://dx.doi.org/10.1186/s13046-019-1131-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458711/
https://www.ncbi.nlm.nih.gov/pubmed/30971297
http://dx.doi.org/10.1186/s13046-019-1131-1

Ejemplares similares