Inhibition of apoptosis signal-regulating kinase by paeoniflorin attenuates neuroinflammation and ameliorates neuropathic pain

BACKGROUND: Neuropathic pain is a serious clinical problem that needs to be solved urgently. ASK1 is an upstream protein of p38 and JNK which plays important roles in neuroinflammation during the induction and maintenance of chronic pain. Therefore, inhibition of ASK1 may be a novel therapeutic appr...

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Detalles Bibliográficos
Autores principales: Zhou, Danli, Zhang, Siqi, Hu, Liang, Gu, Yu-Feng, Cai, Yimei, Wu, Deqin, Liu, Wen-Tao, Jiang, Chun-Yi, Kong, Xiangqing, Zhang, Guang-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458750/
https://www.ncbi.nlm.nih.gov/pubmed/30975172
http://dx.doi.org/10.1186/s12974-019-1476-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458750/
https://www.ncbi.nlm.nih.gov/pubmed/30975172
http://dx.doi.org/10.1186/s12974-019-1476-6

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