DNA methylome profiling of granulosa cells reveals altered methylation in genes regulating vital ovarian functions in polycystic ovary syndrome

BACKGROUND: Women with polycystic ovary syndrome (PCOS) manifest a host of ovarian defects like impaired folliculogenesis, anovulation, and poor oocyte quality, which grossly affect their reproductive health. Addressing the putative epigenetic anomalies that tightly regulate these events is of forem...

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Detalles Bibliográficos
Autores principales: Sagvekar, Pooja, Kumar, Pankaj, Mangoli, Vijay, Desai, Sadhana, Mukherjee, Srabani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458760/
https://www.ncbi.nlm.nih.gov/pubmed/30975191
http://dx.doi.org/10.1186/s13148-019-0657-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458760/
https://www.ncbi.nlm.nih.gov/pubmed/30975191
http://dx.doi.org/10.1186/s13148-019-0657-6

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