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CD103-positive CSC exosome promotes EMT of clear cell renal cell carcinoma: role of remote MiR-19b-3p

BACKGROUND: Clear cell renal cell carcinoma (CCRCC) is characterized by a highly metastatic potential. The stromal communication between stem cells and cancer cells critically influences metastatic dissemination of cancer cells. METHODS: The effect of exosomes isolated from cancer stem cells (CSCs)...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Yang, Guang, Zhao, Danfeng, Wang, Jiaqi, Bai, Yang, Peng, Qiang, Wang, Hongzhi, Fang, Ruizhe, Chen, Guang, Wang, Zhichao, Wang, Keliang, Li, Guangbin, Yang, Yinhui, Wang, Ziqi, Guo, Pengyu, Peng, Li, Hou, Dayong, Xu, Wanhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458839/
https://www.ncbi.nlm.nih.gov/pubmed/30975145
http://dx.doi.org/10.1186/s12943-019-0997-z