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Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress

Tolfenamic acid is a nonsteroidal anti-inflammatory drug with neuroprotective properties, and it alleviates learning and memory deficits in the APP transgenic mouse model of Alzheimer's disease. However, whether tolfenamic acid can prevent motor and memory dysfunction in transgenic animal model...

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Detalles Bibliográficos
Autores principales: Liu, Peng, Li, Yinjie, Yang, Wei, Liu, Danyang, Ji, Xuefei, Chi, Tianyan, Guo, Zhutao, Li, Lin, Zou, Libo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458866/
https://www.ncbi.nlm.nih.gov/pubmed/31049134
http://dx.doi.org/10.1155/2019/4032428