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Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress
Tolfenamic acid is a nonsteroidal anti-inflammatory drug with neuroprotective properties, and it alleviates learning and memory deficits in the APP transgenic mouse model of Alzheimer's disease. However, whether tolfenamic acid can prevent motor and memory dysfunction in transgenic animal model...
Autores principales: | Liu, Peng, Li, Yinjie, Yang, Wei, Liu, Danyang, Ji, Xuefei, Chi, Tianyan, Guo, Zhutao, Li, Lin, Zou, Libo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458866/ https://www.ncbi.nlm.nih.gov/pubmed/31049134 http://dx.doi.org/10.1155/2019/4032428 |
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