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New Insights into the Hepcidin-Ferroportin Axis and Iron Homeostasis in iPSC-Derived Cardiomyocytes from Friedreich's Ataxia Patient

Iron homeostasis in the cardiac tissue as well as the involvement of the hepcidin-ferroportin (HAMP-FPN) axis in this process and in cardiac functionality are not fully understood. Imbalance of iron homeostasis occurs in several cardiac diseases, including iron-overload cardiomyopathies such as Frie...

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Detalles Bibliográficos
Autores principales: Bolotta, Alessandra, Abruzzo, Provvidenza Maria, Baldassarro, Vito Antonio, Ghezzo, Alessandro, Scotlandi, Katia, Marini, Marina, Zucchini, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458886/
https://www.ncbi.nlm.nih.gov/pubmed/31049138
http://dx.doi.org/10.1155/2019/7623023