Biophysical Characterization Platform Informs Protein Scaffold Evolvability

[Image: see text] Evolving specific molecular recognition function of proteins requires strategic navigation of a complex mutational landscape. Protein scaffolds aid evolution via a conserved platform on which a modular paratope can be evolved to alter binding specificity. Although numerous protein...

Descripción completa

Detalles Bibliográficos
Autores principales: Golinski, Alexander W., Holec, Patrick V., Mischler, Katelynn M., Hackel, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458986/
https://www.ncbi.nlm.nih.gov/pubmed/30681831
http://dx.doi.org/10.1021/acscombsci.8b00182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458986/
https://www.ncbi.nlm.nih.gov/pubmed/30681831
http://dx.doi.org/10.1021/acscombsci.8b00182

Ejemplares similares