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Biophysical Characterization Platform Informs Protein Scaffold Evolvability
[Image: see text] Evolving specific molecular recognition function of proteins requires strategic navigation of a complex mutational landscape. Protein scaffolds aid evolution via a conserved platform on which a modular paratope can be evolved to alter binding specificity. Although numerous protein...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458986/ https://www.ncbi.nlm.nih.gov/pubmed/30681831 http://dx.doi.org/10.1021/acscombsci.8b00182 |