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A novel method to address the association between received dose intensity and survival outcome: benefits of approaching treatment intensification at a more individualised level in a trial of the European Osteosarcoma Intergroup

PURPOSE: There is lack of consensus on the prognostic value of received high dose intensity in osteosarcoma survivorship. Many studies have not shown a clear survival benefit when dose intensity is increased. The aim of this study is to go beyond chemotherapy intensification by arm-wide escalation o...

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Detalles Bibliográficos
Autores principales: Lancia, Carlo, Anninga, Jakob K., Sydes, Matthew R., Spitoni, Cristian, Whelan, Jeremy, Hogendoorn, Pancras C. W., Gelderblom, Hans, Fiocco, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458990/
https://www.ncbi.nlm.nih.gov/pubmed/30879111
http://dx.doi.org/10.1007/s00280-019-03797-3