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Interferon-alpha-Induced Changes in NODDI Predispose to the Development of Fatigue

Interferon-alpha (IFN-α) is an important mediator of antiviral immune responses. It is also used clinically in the treatment of hepatitis-C infection. Though effective, IFN-α-based therapies can often impair mood, motivation and cognition, which when severe can appear indistinguishable from major de...

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Detalles Bibliográficos
Autores principales: Dowell, N.G., Bouyagoub, S., Tibble, J., Voon, V., Cercignani, M., Harrison, N.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458994/
https://www.ncbi.nlm.nih.gov/pubmed/29292074
http://dx.doi.org/10.1016/j.neuroscience.2017.12.040