Transcriptomics-Based Screening Identifies Pharmacological Inhibition of Hsp90 as a Means to Defer Aging

Aging strongly influences human morbidity and mortality. Thus, aging-preventive compounds could greatly improve our health and lifespan. Here we screened for such compounds, known as geroprotectors, employing the power of transcriptomics to predict biological age. Using age-stratified human tissue t...

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Detalles Bibliográficos
Autores principales: Janssens, Georges E., Lin, Xin-Xuan, Millan-Ariño, Lluís, Kavšek, Alan, Sen, Ilke, Seinstra, Renée I., Stroustrup, Nicholas, Nollen, Ellen A.A., Riedel, Christian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459000/
https://www.ncbi.nlm.nih.gov/pubmed/30970250
http://dx.doi.org/10.1016/j.celrep.2019.03.044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459000/
https://www.ncbi.nlm.nih.gov/pubmed/30970250
http://dx.doi.org/10.1016/j.celrep.2019.03.044

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