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Transcriptomics-Based Screening Identifies Pharmacological Inhibition of Hsp90 as a Means to Defer Aging
Aging strongly influences human morbidity and mortality. Thus, aging-preventive compounds could greatly improve our health and lifespan. Here we screened for such compounds, known as geroprotectors, employing the power of transcriptomics to predict biological age. Using age-stratified human tissue t...
Autores principales: | Janssens, Georges E., Lin, Xin-Xuan, Millan-Ariño, Lluís, Kavšek, Alan, Sen, Ilke, Seinstra, Renée I., Stroustrup, Nicholas, Nollen, Ellen A.A., Riedel, Christian G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459000/ https://www.ncbi.nlm.nih.gov/pubmed/30970250 http://dx.doi.org/10.1016/j.celrep.2019.03.044 |
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