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Necroptotic Cell Death Promotes Adaptive Immunity Against Colonizing Pneumococci
Pore-forming toxin (PFT) induced necroptosis exacerbates pulmonary injury during bacterial pneumonia. However, its role during asymptomatic nasopharyngeal colonization and toward the development of protective immunity was unknown. Using a mouse model of Streptococcus pneumoniae (Spn) asymptomatic co...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459137/ https://www.ncbi.nlm.nih.gov/pubmed/31019504 http://dx.doi.org/10.3389/fimmu.2019.00615 |