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Silencing UBE4B induces nasopharyngeal carcinoma apoptosis through the activation of caspase3 and p53

AIM: The human ubiquitination factor E4B (UBE4B) gene is frequently amplified in some solid cancers. However, the role of UBE4B in nasopharyngeal carcinoma (NPC) has not yet been investigated. METHODS: Firstly, we analyzed the expression of UBE4B in NPC samples using real-time quantitative PCR and W...

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Detalles Bibliográficos
Autores principales: Weng, Chengyin, Chen, Yong, Wu, Yong, Liu, Xia, Mao, Haibo, Fang, Xisheng, Li, Baoxiu, Wang, Lina, Guan, Mingmei, Liu, Guolong, Lu, Lin, Yuan, Yawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459139/
https://www.ncbi.nlm.nih.gov/pubmed/31040698
http://dx.doi.org/10.2147/OTT.S196132