PEGylated and CD47-conjugated nanoellipsoidal artificial antigen-presenting cells minimize phagocytosis and augment anti-tumor T-cell responses

PURPOSE: Antigen-presenting cells (APCs) are powerful tools to expand antigen-specific T cells ex vivo and in vivo for tumor immunotherapy, but suffer from time-consuming generation and biosafety concerns raised by live cells. Alternatively, the cell-free artificial antigen-presenting cells (aAPCs)...

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Detalles Bibliográficos
Autores principales: Song, Shilong, Jin, Xiaoxiao, Zhang, Lei, Zhao, Chen, Ding, Yan, Ang, Qianqian, Khaidav, Odontuya, Shen, Chuanlai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459144/
https://www.ncbi.nlm.nih.gov/pubmed/31040669
http://dx.doi.org/10.2147/IJN.S195828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459144/
https://www.ncbi.nlm.nih.gov/pubmed/31040669
http://dx.doi.org/10.2147/IJN.S195828

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