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PEGylated and CD47-conjugated nanoellipsoidal artificial antigen-presenting cells minimize phagocytosis and augment anti-tumor T-cell responses

PURPOSE: Antigen-presenting cells (APCs) are powerful tools to expand antigen-specific T cells ex vivo and in vivo for tumor immunotherapy, but suffer from time-consuming generation and biosafety concerns raised by live cells. Alternatively, the cell-free artificial antigen-presenting cells (aAPCs)...

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Detalles Bibliográficos
Autores principales:	Song, Shilong, Jin, Xiaoxiao, Zhang, Lei, Zhao, Chen, Ding, Yan, Ang, Qianqian, Khaidav, Odontuya, Shen, Chuanlai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459144/ https://www.ncbi.nlm.nih.gov/pubmed/31040669 http://dx.doi.org/10.2147/IJN.S195828

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