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Small airway hyperresponsiveness in COPD: relationship between structure and function in lung slices

The direct relationship between pulmonary structural changes and airway hyperresponsiveness (AHR) in chronic obstructive pulmonary disease (COPD) is unclear. We investigated AHR in relation to airway and parenchymal structural changes in a guinea pig model of COPD and in COPD patients. Precision-cut...

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Detalles Bibliográficos
Autores principales: Maarsingh, Harm, Bidan, Cécile M., Brook, Bindi S., Zuidhof, Annet B., Elzinga, Carolina R.S., Smit, Marieke, Oldenburger, Anouk, Gosens, Reinoud, Timens, Wim, Meurs, Herman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459292/
https://www.ncbi.nlm.nih.gov/pubmed/30628486
http://dx.doi.org/10.1152/ajplung.00325.2018