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Molecular mechanisms and pathobiology of oncogenic fusion transcripts in epithelial tumors

Recurrent fusion transcripts, which are one of the characteristic hallmarks of cancer, arise either from chromosomal rearrangements or from transcriptional errors in splicing. DNA rearrangements include intrachromosomal or interchromosomal translocation, tandem duplication, deletion, inversion, or r...

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Detalles Bibliográficos
Autores principales: Tuna, Musaffe, Amos, Christopher I., Mills, Gordon B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459343/
https://www.ncbi.nlm.nih.gov/pubmed/31007851
http://dx.doi.org/10.18632/oncotarget.26777