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The immune checkpoint molecules PD-1, PD-L1, TIM-3 and LAG-3 in diffuse large B-cell lymphoma

Signaling through immune checkpoint receptors may lead to T-cell exhaustion and function as immune escape mechanisms in cancer. For diffuse large B-cell lymphoma (DLBCL), the mechanistic and prognostic importance of these markers on tumor cells and the tumor microenvironment remains unclear. We dete...

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Detalles Bibliográficos
Autores principales: Chen, Benjamin J., Dashnamoorthy, Ravi, Galera, Pallavi, Makarenko, Vladislav, Chang, Hong, Ghosh, Srimoyee, Evens, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459346/
https://www.ncbi.nlm.nih.gov/pubmed/31007846
http://dx.doi.org/10.18632/oncotarget.26771