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Synthetic surfactin analogues have improved anti-PEDV properties

Surfactin has antiviral activity against various enveloped viruses by inhibiting viral membrane fusion. However, the potential utility of surfactin as an antiviral drug is limited by its cytotoxicity. In this study, 10 surfactin analogues were obtained by chemical synthesis and evaluated to determin...

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Detalles Bibliográficos
Autores principales: Yuan, Lvfeng, Zhang, Shuai, Peng, Jie, Li, Yuchen, Yang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459484/
https://www.ncbi.nlm.nih.gov/pubmed/30973929
http://dx.doi.org/10.1371/journal.pone.0215227