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Protective role of the deSUMOylating enzyme SENP3 in myocardial ischemia-reperfusion injury

Interruption of blood supply to the heart is a leading cause of death and disability. However, the molecular events that occur during heart ischemia, and how these changes prime consequent cell death upon reperfusion, are poorly understood. Protein SUMOylation is a post-translational modification th...

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Detalles Bibliográficos
Autores principales: Rawlings, Nadiia, Lee, Laura, Nakamura, Yasuko, Wilkinson, Kevin A., Henley, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459529/
https://www.ncbi.nlm.nih.gov/pubmed/30973885
http://dx.doi.org/10.1371/journal.pone.0213331