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Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer’s disease

Alzheimer’s disease currently lacks treatment options that effectively reverse the biological/anatomical pathology and cognitive deficits associated with the disease. Loss of function of the nuclear receptor REV-ERB is associated with reduced cognitive function in mouse models. The effect of enhance...

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Detalles Bibliográficos
Autores principales:	Roby, Deborah A., Ruiz, Fernanda, Kermath, Bailey A., Voorhees, Jaymie R., Niehoff, Michael, Zhang, Jinsong, Morley, John E., Musiek, Erik S., Farr, Susan A., Burris, Thomas P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459530/ https://www.ncbi.nlm.nih.gov/pubmed/30973894 http://dx.doi.org/10.1371/journal.pone.0215004

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